As we know, exercise in itself together with its benefits are of course very advantageous for an individual. However, everything that comes too much can also generate something that's adverse and can sometimes cost a life.
It has been a common knowledge that being fit by means of exercise actually helps us to prevent a number of diseases that just awaits us. Some of these benefits include but not limited to a reduced risk of type 2 diabetes, osteoporosis and hypertension to name a few.
But recently, in the pursuit of finding out various instances whether endurance exercise can generate adverse health impacts, Dr. Jeffrey Towbin together with his colleagues at the Cincinnati Children's Hospital Medical Center, have been investigating about it.
The said investigation that was published in the American Journal of Physiology - Heart and Circulatory Physiology, aimed to figure out the various health impacts of endurance exercise on arrhythmogenic ventricular cardiomyopathy.
Arrhythmogenic ventricular cardiomyopathy
Arrhythmogenic ventricular cardiomyopathy (AVC) is a rare-occurring genetic disorder, which usually affects the structural integrity of the heart wall. Commonly regarded as a condition where it can suddenly lead to a cardiac death during a course of an intense exercise, AVC can also be a quiet enemy to a point that an individual can endure a major cardiac collapse.
The role of desmoplakin
Desmoplakin, is a kind of protein which is an important component of desmosomes - a protein that connects the cells within the heart's wall. During the previous studies, it has been proven that mice with mutated forms of desmoplakin have acquired identical symptoms to human AVC.
But in their latest research, Dr. Towbin together with his colleagues has found that conducting various endurance exercise actually brings about an earlier start of AVC symptoms.
Meanwhile, Medical News Today revealed future studies about AVC seems to have been set in place with an objective to find out its deeper nature and likely to come up with new set of tests for an early detection.
