Oct 11, 2014 02:16 PM EDT
Insulin Resistance Breakthrough: Is this the Cure for Diabetes?

A new scientific discovery could just be the cure for Diabetes. The discovered treatment involves the blocking of VEGF-B, a protein that is responsible for the buildup of fat around the wrong places in the body, consequently causing the Type II Diabetes.

Professor Ulf Eriksson, head of the scientific research, carried out the research on mice at the Karolinska Institute, Sweden, the Ludwig Institute for Cancer Research, which is based in New York. Professor Ulf Eriksson said that the discovery represented a potential breakthrough in the treatment of Diabetes. "It's a great feeling to present these results. We discovered VEGF-B back in 1995, and since then the VEGF-B project has been a lengthy sojourn in the wilderness, but now we're making one important discovery after the other."

The professor said that in their current study, they had shown that VEGF-B inhibition can be used to treat and even prevent type II Diabetes. He also stated that it could be done for drug candidates.

Type II diabetes occurs when a person becomes obese. Insulin resistance follows the obesity, after which diabetes comes. The cells fail to respond to insulin properly. The glucose does not enter the cells and blood glucose levels rise.

Diabetes type II is a common ailment posing a serious global concern. Analysts project that by 2030, over half a billion people will be living with the disease.

The experiment was carried out in mice. The researchers noted that diabetes induced mice given 2H10, an antibody that inhibits the actions of VEGF-B, did not develop insulin resistance, hence did not develop diabetes. The researcher also found that interbreeding these rats with those that could not naturally produce VEGF-B, the offspring of the two breeds of mice never developed diabetes.

The research could just be what scientists need in their experiments for finding the cure for diabetes.

 PREVIOUS POST
NEXT POST