On Sunday, Ed Sheeran's charity benefit show in Malibu became the most star studded area in the world as it was attended by numerous famous faces.

Rock 4 EB was held in a 90 minute concert to benefit the Epidermolysis Bullosa Medical Research Foundation, which aims to help the sufferers of epidermolysis bullosa (EB), a life threatening and incurable skin disorder.

The event was attended by numerous famous faces, including 'The Big Bang Theory' star Kaley Cuoco, from 'Scandal' Scott Foley, 'Modern Family' Ed O'Neill, 'Desperate Housewives' star Teri Hatcher, Nina Dobrev of 'The Vampire Diaries,' 'American Idol' judge Randy Jackson, 'Avengers: Age of Ultron' Aaron Taylor-Johnson, 'Fifty Shades of Grey' director Sam Taylor-Johnson, supermodel Cindy Crawford and husband Randy Gerber, 'Friends' star Courtney Cox and many more.

According to Los Angeles Times nearly 500 people showed up at the event to show their support for the benefit concert. They enjoyed the night while savoring the served food that included caviar, three types of hot dogs, cupcakes, veggies burgers and many more.

During the event, while on stage Ed Sheeran urged the attendees to enjoy and celebrate the night, "I think as long as you just enjoy yourselves, I will enjoy myself as well," the 'Photograph' singer said. "What I find sometimes about these events is people are scared to sing. They're scared to clap. They don't know what they're allowed to do. I just say as long as you feel happy doing it, don't worry about what the person next to you thinks."

The event was hosted by Hollywood funnyman David Spade, who rock the night with his simple outfit. Donning a black shirt and black coat as he posed for snapshots with several actresses.

After the star studded event, Kaley who recently split from Ryan Sweeting posted a video on Instagram and captioned it "Thank you @edsheeeran for being an amazing human, an amazing musician and playing for some incredible, well deserving kids tonight (and adults) #rock4EB #findacure."