On Saturday night, Rosie O’Donnell a comedian had a show at Gotham Comedy Club in New York City. She touched on the issues concerning her estranged daughter, Chelsea O'Donnell.

During the gig, Rosie had this to say,"I love all of my kids. My daughter has been in the news. It's been in the news, but it's not news to the family. It's been a decade long.' Adding she said, 'As Mom, my wish is for love and peace and wait until it's done."

O'Donnell explained that, “Chelsea just turned 18. For adopted children 18 is a magic number,” she added. “At 18 they’re gonna rebel any way they can, any way they can get your attention.”

Rosie however defended Chelsea, who she said had a “chemical imbalance.”

Last week, a source close to Rosie also revealed that O’Donnell is “extremely depressed,” a matter that O’Donnell shed light on during her set.

“I know about mental illness — I have my own,” the former daytime host admitted. “I thought mental illness was failure of my character, not my chemistry.”

The 53-year-old shared that it started when she was 20-year-old, and that she’s currently on antidepressents.

These are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive compulsive disorder, eating disorders, chronic pain, neuropathic pain.

In an interview with the Daily Mail earlier this month, Chelsea called Rosie “not genuine,” which Rosie later referred to as “heartbreaking on every level.”

Currently, Chelsea is living with Steve Sheerer the 26-year-old man she met on Tinder. Police found her with him in his family home in Barnegat Township, New Jersey last August 18 after she reportedly left Rosie’s home.

This came after Chelsea left Rosie’s care when she turned 18 years old to spend time with her birth mother, Deanna Micoley.

On Thursday, October 15, Rosie who formerly co-hosted, The View was sued by a former senior producer of the show for slander. This month hasn't been truly easy for Rosie!