Two of the biggest young actors working in Hollywood right now, "The Social Network" Oscar nominee Jesse Eisenberg and "Twilight" actress Kristen Stewart, have joined forces again after their 2009 film "Adventureland" co-starring Ryan Reynolds and Kristen Wiig - but now they tackle on FULL comedy in the "Amerian Ultra Red Band" trailer!

Their previous film together, "Adventureland," was basically a romantic dramedy, but now the "American Ultra Red Band" trailer shows a whole different side of their relationship as they play a stoner couple terrified after discovering he's something like a train assassin with a lot of martial arts moves.

Watch the hilarious "American Ultra Red Band" trailer below, also featuring "That 70s Show" star Topher Grace and John Leguizamo from "Chef"!